The GENOMAVIR® target discovery process consists of 4-steps:

1. Gene trapping to create clones of cells producing unique fusion proteins with a common fluorescent domain under the control of cellular promoters.
2. FACS analysis and sorting of cells to fractionate by level of protein expression.
3. High-throughput sequencing of specific insertion sites responsible for the creation of the fusion proteins identified by FACS analysis using SAVI, a NewLink Genetics proprietary technology.
4. Construction of a relational database to combine these data in a format easily interfaced with available bioinformatics software such as NewLink Genetics’ Vmatch and GeneSeqer to identify potential targets for evaluation as either diagnostic markers or drug based therapeutic interventions.